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| SPECT Radiopharmaceuticals | ||
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Most of the SPECT procedures are based on 99mTc.
Traditionally technetium chemistry is dominated by [Tc=O] oxo core. The
first generation 99mTc radiopharmaceuticals are based on
highly sensitive but non-specific “catch-all” approach such as
99m Tc-MDP
bone scans. Second generation 99mTc radiopharmaceuticals are
based on “catch-one” approach
and these are highly sensitive and highly specific.
Many of the second generation 99mTc radiopharmaceuticals based on new cores such as [Tc≡N]2+ core, [Tc(CO)3]+ core, and [Tc]HYNIC core. |
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